Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact <i>Caenorhabditis elegans</i> Development and Reproductive Behavior.
Int J Mol Sci – March 26, 2025
Source: PubMed Central
Summary
Surprisingly, even tiny, non-lethal amounts of designer drugs like 2C-I and 25I-NBOMe can profoundly alter basic life functions. Researchers successfully demonstrated how these compounds impact the development and reproductive behavior of *C. elegans* worms. Through careful observation, it was clearly shown that exposure caused significant delays in the worms' growth and maturation. Moreover, the drugs noticeably disrupted their natural mating patterns. These compelling findings reveal the potent biological effects of these substances on living organisms, influencing critical life stages and behaviors.
Abstract
Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact Caenorhabditis elegans Development and Reproductive Behavior.