Reactivations Associated with the Use of 5-MeO-DMT Among Spanish-Speaking Individuals: Prevalence, Predictors, and Emotional Valence.

J Psychoactive Drugs  – October 23, 2025

Source: PubMed

Summary

A significant number of individuals who use 5-MeO-DMT report 'reactivations' – spontaneous, brief re-experiences of its effects. A survey among Spanish-speaking individuals investigated how common these re-experiences are, what predicts them, and their emotional impact. Results indicate reactivations are prevalent, often linked to higher doses, and notably, are frequently viewed as positive or neutral, enhancing feelings of well-being. This suggests these occurrences are generally not distressing.

Abstract

Reactivations Associated with the Use of 5-MeO-DMT Among Spanish-Speaking Individuals: Prevalence, Predictors, and Emotional Valence.

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