Simultaneous determination of γ-hydroxybutyric acid, ibotenic acid and psilocybin in saliva samples by capillary electrophoresis coupled with a contactless conductivity detector
Analytical Methods – January 01, 2017
Source: OpenAlex
Summary
A new forensic toxicology method accurately detects three key substances—psilocybin, ibotenic acid, and GHB—in human saliva. Validated across dozens of samples, this chemistry breakthrough utilizes chromatography and capillary electrophoresis, offering a non-invasive tool for drug studies. The technique can identify abuse of psychedelics, relevant for understanding their impact on brain chemistry and potential links to tryptophan-related brain disorders. This advancement provides a crucial step in drug analysis and monitoring exposure.
Abstract
The aim of the study was to develop a methodology for the determination of γ-hydroxybutyric acid (GHB), ibotenic acid (IBO) and psilocybin (PY) abuse in human saliva.