Management of overdoses of salvia, kratom, and psilocybin mushrooms: a literature review

Expert Review of Clinical Pharmacology  – July 10, 2020

Source: OpenAlex

Summary

Global data reveal a significant rise in emergency room visits related to Salvia, kratom, and psilocybin mushroom use. While not typically fatal, health care professionals in medicine, including psychiatry and intensive care, must be prepared to assess and manage such overdose scenarios. Understanding the pharmacological properties of these substances, many of which are alkaloids with a history in traditional medicine, is crucial. This knowledge, often found in resources like CINAHL, informs appropriate patient care and highlights the ongoing need for chemical synthesis and alkaloids research to guide treatment.

Abstract

Salvia, kratom, and psilocybin mushrooms may not be an initial consideration when healthcare practitioners are triaging an overdose scenario; however, data from around the world demonstrate an increased use of these agents. While not typically fatal, clinicians must be prepared to assess these as a potential etiology of overdoses and provide appropriate supportive care.

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