Hypnotic Induction of the Interference of Psilocybin with Optically Induced Spatial Distortion
Pharmacopsychiatry – November 01, 1969
Source: OpenAlex
Summary
A compelling finding in Psychology and Neuroscience indicates that an individual's perceptual stability is a personality invariant, persisting even under the hallucinogen Psilocybin and hypnotic induction. This small study, involving four individuals given 160–200 µg/kg psilocybin (a chemical synthesis and alkaloid), explored its effect on spatial distortion thresholds. It suggests personality structure dictates perceptual reproducibility, showing minimal Interference from drug-induced changes. This work contributes to Psychedelics and Drug Studies, demonstrating how neurotransmitter receptor influence on behavior doesn't alter this core stability, offering insights for Medicine beyond simple music distortion.
Abstract
The influence of personality structure on the stability of perceptual performance, specifically the degree of reproducibility under hypnotic induction of the psilocybinproduced lowering of spatial distortion thresholds, was investigated in two "variable" and two "stable" psilocybin reactors, that is, subjects who displayed variable and stable MMPI profiles under both control conditions and the influence of 160–200 µg/kg psilocybin. The results indicate that degree of stability in perceptual performance is a personality invariant with or without drug and also during the hypnotically-induced psilocybin experience. Moreover, susceptibility to hypnotic induction and ability to replicate exactly the hypnotically induced perceptual task are unrelated.