Neural correlates of the personality factor openness before and after psilocybin-therapy to depressed patients
Zenodo (CERN European Organization for Nuclear Research) – August 31, 2019
Source: OpenAlex
Summary
Unlocking the brain's capacity for change, clinical psychology explores how psilocybin can reshape personality. This work in Psychology and Psychedelics and Drug Studies investigates how "Openness to experience" and its neural correlates of consciousness shift in treatment-resistant depression. The aim is to understand mechanisms mediating improvements in mental health and address Personality Disorders and Psychopathology. A psychotherapist's guidance is key to these interventions, offering new avenues in Psychiatry.
Abstract
This document is my Master's Thesis for the Research Master Cognitive Neuroscience program at Maastricht University. The present study investigated the relationship between openness and its neural correlates in treatment-resistant depression preceding and following a psilocybin-assisted intervention, to (i) extent the findings of personality neuroscience from healthy to depressed population and (ii) unfold the neural mechanisms that could be mediating clinical improvements.