The History of Psychedelics in Psychiatry
Pharmacopsychiatry – December 07, 2020
Source: OpenAlex
Summary
The historical understanding of hallucinogens has dramatically shifted. Early 20th-century psychiatry explored mescaline to model psychosis, seeking to understand the underlying basis of mental disorders. Following LSD's discovery in 1943, the focus in psychology evolved. Modern drug studies highlight the therapeutic value of psychedelics as adjuncts to psychotherapy. Psychotherapists now consider these compounds, often derived from chemical synthesis or alkaloids, for their potential in mental health. This represents a significant pivot from early psychoanalysis, moving towards complementary approaches in psychiatry, away from merely inducing psychosis-like states.
Abstract
Abstract Initial interest in the value of psychedelic drugs (“psychotomimetics”) in psychiatry began in the early 20th century, with explorations of the possibility that mescaline or peyote could produce psychosis-like effects. Over time, interest was focused on whether the effects of psychedelics could inform as to the underlying basis for psychiatric disorders. As research continued, and especially after the discovery of LSD in 1943, increasing interest in a role for psychedelics as adjuncts to psychotherapy began to evolve and became the major focus of work with psychedelics up to the present day.