metapsy-project/data-depression-psiloctr: Version 25.1.1

Zenodo (CERN European Organization for Nuclear Research)Β  – November 18, 2025

Source: OpenAlex

Summary

A crucial living database now rigorously tracks evidence on psilocybin-assisted therapies for depression. This comprehensive data collection, meticulously extracted by two independent experts, forms a meta-analytic research domain for understanding treatment outcomes. It provides detailed effect sizes for post-test and long-term follow-ups, adhering to a Metapsy data standard. Leveraging computer science principles, this resource facilitates sophisticated mathematical analysis of therapy comparisons. Such structured data could also inform future artificial intelligence applications, advancing mental health interventions. This ongoing effort offers a vital, updated resource for therapeutic insights.

Abstract

The data-depression-psiloctr dataset πŸ“Š The data-depression-psiloctr dataset is a meta-analytic research domain (MARD) on psilocybin-assisted therapies for adults with depressive symptoms. This MARD is part of the Metapsy project. The date of the last search update is provided here. This dataset includes psilocybin-assisted therapy vs. control ('psy vs ctr') comparisons. Effect sizes are provided for outcomes at post-test and long-term follow-ups, if available. This living database has been developed by the Sypres (Synthesis of Psychedelic Research Studies) Collaboration. Further information on Sypres and its underlying methodology can be found in this published article. The dataset follows the Metapsy data standard. All included information has been independently extracted two researchers. Risk of bias ratings were conducted using the Cochrane Collaboration Risk of Bias Tool (Version 2).

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