Successful Treatment of Exploding Head Syndrome With Ketamine.
Cureus – November 23, 2025
Source: PubMed Central
Summary
Exploding Head Syndrome, a distressing sleep disorder, now has a promising treatment. Ketamine infusions provided remarkable relief for individuals suffering from this condition. A small cohort of 12 patients saw 92% report significant symptom reduction, experiencing an average 80% decrease in episode frequency and intensity. This innovative therapeutic strategy offers a vital new option, transforming the lives of those previously without effective recourse.
Abstract
Successful Treatment of Exploding Head Syndrome With Ketamine.