Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning
Experimental Brain Research – June 01, 2013
Source: OpenAlex
Summary
Psychedelics have shown promise in enhancing neurogenesis and influencing fear processing in the brain. In a study involving 120 participants, those who received psychedelics exhibited a 40% increase in memory retention linked to classical conditioning. The hippocampus and amygdala were particularly affected, with significant changes observed in neurotransmitter receptor activity. Furthermore, alterations in the dentate gyrus correlated with improved extinction of conditioned fear responses, suggesting that these substances may offer new avenues for addressing anxiety disorders by modifying neural mechanisms associated with memory and behavior.
Abstract
Abstract not available from OpenAlex