Chromosomal Abnormalities in Leukocytes from LSD-25 Users
Science – July 21, 1967
Source: OpenAlex
Summary
LSD-25 users exhibited a striking 75% rate of chromosomal abnormalities in their leukocytes, compared to just 11% among nonusers. Out of eight LSD users, six displayed significant genetic damage, while only one of nine controls showed similar issues. Notably, the two users without detectable damage had the lowest estimated average doses. Testing occurred between one day and six months post-LSD-25 use, highlighting potential long-term effects on DNA repair mechanisms and raising concerns about the drug's impact on genetic stability and overall health.
Abstract
A significant increase of chromosomal abnormalities was found in leukocytes from LSD-25 users (six out of eight) compared to nonuser controls (one out of nine). The two LSD-25 users showing no damage reported the lowest estimated average dose. The subjects whose cells showed damage were tested between 1 day and 6 months after their last LSD-25 dose.