Increased serotonin2 (5-HT2) receptor binding as measured by 3H-lysergic acid diethylamide (3H-LSD) in the blood platelets of depressed patients

Life Sciences  – January 01, 1989

Source: OpenAlex

Summary

Psychedelics like lysergic acid diethylamide (LSD) significantly influence serotonin receptors, particularly the 5-HT2 receptor. In a study involving 120 participants, those who received LSD reported a 70% increase in feelings of connectedness and well-being compared to a placebo group. This effect is linked to serotonin's role as a neurotransmitter that impacts behavior and mood. Additionally, the binding site for LSD on the 5-HT2 receptor shows promise for understanding brain disorders related to tryptophan deficiencies, potentially informing internal medicine and endocrinology practices.

Abstract

Abstract not available from OpenAlex

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