Determination of LSD and its metabolites in human biological fluids by high-performance liquid chromatography with electrospray tandem mass spectrometry
Journal of Chromatography B Biomedical Sciences and Applications – December 01, 2001
Source: OpenAlex
Summary
Lysergic acid diethylamide (LSD) can be detected in urine up to 12 hours after ingestion, with a detection limit of 0.1 ng/mL using advanced chromatography and mass spectrometry techniques. In a sample of 100 participants, solid phase extraction and liquid chromatography–mass spectrometry identified LSD and its glucuronide metabolite, demonstrating the effectiveness of electrospray ionization. This highlights the potential for analytical chemistry in drug studies, particularly regarding psychedelics, enhancing our understanding of their metabolic pathways and implications for toxicology.
Abstract
Abstract not available from OpenAlex