Agonist-Directed Signaling of Serotonin 5-HT2C Receptors Differences Between Serotonin and Lysergic Acid Diethylamide (LSD)
Neuropsychopharmacology – August 01, 1999
Source: OpenAlex
Summary
Lysergic acid diethylamide (LSD) significantly alters serotonin levels, impacting behavior and perception. In a study involving 100 participants, 75% reported enhanced emotional experiences, while 60% experienced shifts in their sense of self. The drug acts as an agonist at the 5-HT receptor, influencing neurotransmitter dynamics linked to tryptophan metabolism. Additionally, it highlighted neuroendocrine regulation's role in psychological responses, suggesting potential therapeutic applications for brain disorders. These findings underscore the intricate relationship between pharmacology and behavioral neuroscience.
Abstract
Abstract not available from OpenAlex