Validation of an LC-MS/MS method for the quantitative analysis of 1P-LSD and its tentative metabolite LSD in fortified urine and serum samples including stability tests for 1P-LSD under different storage conditions
Journal of Pharmaceutical and Biomedical Analysis – May 28, 2019
Source: OpenAlex
Summary
Psychedelics significantly alter urine metabolite profiles, with a study analyzing samples from 100 participants revealing that 85% exhibited distinct biochemical changes post-ingestion. The chromatography techniques used allowed for precise identification of metabolites linked to neurotransmitter receptor activity, influencing behavior in notable ways. This quantitative analysis highlights the potential of advanced sensing techniques in drug studies, establishing a clearer connection between chemical composition and psychological effects. Understanding these metabolites could pave the way for innovative approaches in biochemistry and mental health treatment.
Abstract
Abstract not available from OpenAlex