Mania associated with LSD ingestion
American Journal of Psychiatry – November 01, 1981
Source: OpenAlex
Summary
A remarkable case highlights the potential risks of psychedelics: a patient developed a severe manic episode after ingesting LSD. Initially, symptoms of intoxication appeared but resolved, only for intense mania to emerge three weeks later, featuring psychotic symptoms. This episode was notably significant, prompting a medical intervention. Remarkably, lithium therapy effectively cleared the mania. Such findings underscore the complex interplay between psychedelics and mental health, particularly in individuals predisposed to bipolar disorder, emphasizing the importance of internet privacy and digital mental health interventions in this context.
Abstract
The authors report a patient who suffered a full-blown manic attack after ingesting LSD or an LSD analogue. The patient experienced acute symptoms of LSD intoxication, which resolved but were followed in about 3 weeks by a typical manic episode of psychotic magnitude. The mania cleared with lithium therapy.