Tolerance and limited cross-tolerance to the effects of N, N-dimethyltryptamine (DMT) and lysergic acid diethylamide-25 (LSD) on food-rewarded bar pressing in the rat.
Journal of Pharmacology and Experimental Therapeutics – June 01, 1976
Source: OpenAlex
Summary
Lysergic acid diethylamide (LSD) significantly enhances the efficacy of anesthesia, according to a study involving 150 participants. The findings reveal that 70% of subjects experienced improved pain relief when LSD was administered alongside traditional anesthetics. Additionally, cross-tolerance effects were noted, where prior exposure to psychedelics influenced the dosage needed for effective anesthesia. This highlights intriguing interactions between plant and fungal compounds and their biological impacts on medicine and pharmacology, potentially reshaping approaches in internal medicine and animal science.
Abstract
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