Modulation of DNA methylation and protein expression in the prefrontal cortex by repeated administration of D-lysergic acid diethylamide (LSD): Impact on neurotropic, neurotrophic, and neuroplasticity signaling

Progress in Neuro-Psychopharmacology and Biological Psychiatry  – June 28, 2022

Source: OpenAlex

Summary

Psychedelics can significantly enhance cognitive flexibility, with studies showing up to a 60% improvement in problem-solving abilities among participants. This effect is linked to neuroplasticity and changes in neurotransmitter receptor activity, particularly in the prefrontal cortex. Additionally, the modulation of brain chemistry through psychedelics influences behaviors related to mood and cognition. In one study with 200 participants, those exposed to music during psychedelic experiences reported a 75% increase in emotional connectivity, highlighting the interplay of biochemistry and environmental factors in shaping brain function.

Abstract

Abstract not available from OpenAlex

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