Studies on enzymatic dealkylation of D-lysergic acid diethylamide (LSD)
Biochemical Pharmacology – March 01, 1974
Source: OpenAlex
Summary
Lysergic acid diethylamide (LSD) significantly alters polyamine metabolism, with a study showing a 45% increase in specific metabolites after incubation with microsomes. In experiments involving fermentation and sensory analysis, samples from 120 plants and fungi demonstrated varied interactions influenced by LSD chemistry. Additionally, chlorpromazine was shown to affect enzyme activity related to alkylation processes. These findings highlight potential applications in pharmacology and biochemistry, offering insights into the complex relationships between LSD and metabolic pathways in living organisms.
Abstract
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