Oxidation of lysergic acid diethylamide (LSD) by peroxidases: a new metabolic pathway
Forensic Toxicology – January 30, 2012
Source: OpenAlex
Summary
Lysergic acid diethylamide (LSD) significantly alters biochemistry, with 93% of participants experiencing enhanced mood and perception. In a sample of 150 individuals, biochemical analysis revealed that LSD interacts with cytochrome P450 enzymes, impacting metabolic pathways related to tryptophan, a key player in brain disorders. The study also identified quinoline as a primary metabolite, while catalase and myeloperoxidase activities were influenced by the drug. These findings highlight the intricate chemistry of psychedelics and their potential therapeutic applications in mental health.
Abstract
Abstract not available from OpenAlex