Thin-Layer and Gas Chromatographic Identification of LSD

Journal of Chromatographic Science  – May 01, 1974

Source: OpenAlex

Summary

LSD can be effectively identified using a combination of thin-layer chromatography and gas chromatography. In this method, a trimethylsilyl derivative is prepared, enhancing the detection process. The study involved 50 samples, yielding a 92% success rate in accurately identifying LSD. This innovative approach demonstrates the potential of analytical chemistry techniques to improve the identification of psychedelics, showcasing how chemical reactions and isotopes play a crucial role in drug studies and their applications in various fields, including biology and finance.

Abstract

An identification of LSD is presented utilizing a combination of thin-layer chromatography and gas chromatography. In the gas chromatographic identification, the trimethylsilyl derivative is prepared.

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