Lysergic Acid Diethylamide (Lsd-25): Ix. Effect on Snails
The Journal of Psychology – October 01, 1955
Source: OpenAlex
Summary
Certain snail species exhibit sensitivity to lysergic acid diethylamide (LSD-25) comparable to that of Siamese fighting fish. Specifically, Ambularia cuprina, or the Mystery Snail, displays persistent, disorganized movement after LSD-25 exposure, lasting for several hours and significantly altering its behavior. In contrast, D-1-bromlysergic acid diethylamide (BOL-148) does not induce similar effects. These findings suggest that snails could serve as effective models for assessing the pharmacological effects of LSD-25 under specific conditions, highlighting their utility in psychology and zoology.
Abstract
"Certain species of snails are at least as sensitive to lysergic acid diethylamide (LSD-25) as are the Siamese fighting fish (Betta splendens). Ambularia cuprina (Mystery Snail) responds to LSD-25 with a typical, persistent, disorganized movement of the gastropod. This movement persists many hours and markedly alters the behavior of the snail. D-1-bromlysergic acid diethylamide (BOL-148) does not show the same effect. The snail may be used to assay LSD-25 under certain conditions." (PsycINFO Database Record (c) 2005 APA, all rights reserved).