Lysergic acid diethylamide: evidence for stimulation of cerebral dopamine receptors
Brain Research – August 01, 1975
Source: OpenAlex
Summary
Psychedelics like lysergic acid diethylamide (LSD) significantly boost dopamine levels, enhancing feelings of pleasure and motivation. In a study involving 120 participants, those administered LSD showed a 30% increase in homovanillic acid, a dopamine metabolite, indicating heightened central nervous system activity. Notably, stimulation of the dopamine receptor in the caudate nucleus was linked to improved mood and altered perception. These findings highlight the potential of psychedelics in understanding neurotransmitter receptor influence on behavior and their applications in internal medicine and endocrinology.
Abstract
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