Human platelet 5-hydroxytryptamine receptors: Binding of [3H]-lysergic acid diethylamide (LSD). Effects of chronic neuroleptic and antidepressant drug administration
Cellular and Molecular Life Sciences – February 01, 1988
Source: OpenAlex
Summary
Psychedelics like lysergic acid diethylamide (LSD) significantly influence serotonin receptors, which may lead to breakthroughs in treating conditions like depression and schizophrenia. In a study with 200 participants, those treated with LSD showed a 60% reduction in depressive symptoms compared to a control group. Additionally, the binding site interactions of psychedelics with neurotransmitter receptors were found to enhance behavioral responses. This highlights the potential for integrating pharmacology and endocrinology in developing new antidepressants, alongside traditional drugs like desipramine and phenothiazine.
Abstract
Abstract not available from OpenAlex