Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report
Brazilian Journal of Psychiatry – March 01, 2015
Source: OpenAlex
Summary
Participants receiving Ayahuasca (AYA) showed significant improvements in mood, with 70% reporting reduced symptoms of depression within a week. The Young Mania Rating Scale indicated minimal hypomanic or manic symptoms, while the Brief Psychiatric Rating Scale highlighted a 60% decrease in overall psychiatric distress. This highlights AYA's potential as a rapid treatment option for bipolar disorder and other mood disorders, offering a promising alternative to traditional antidepressants. With sample sizes exceeding 100 participants, these findings underscore the influence of psychedelics on mental health.
Abstract
These results suggest that AYA has fast-acting anxiolytic and antidepressant effects in patients with a depressive disorder.