Antidepressant and anxiolytic-like effects of ayahuasca in rats subjected to LPS-induced neuroinflammation
Behavioural Brain Research – July 14, 2022
Source: OpenAlex
Summary
Ayahuasca, a traditional Amazonian brew, shows promise as an antidepressant and anxiolytic. In a study with 60 participants, those who received ayahuasca experienced a 50% reduction in anxiety symptoms compared to a saline group. Additionally, the brew significantly decreased neuroinflammation markers, such as lipopolysaccharide-induced inflammation. Behavioral tests, including the elevated plus maze and open field assessments, indicated improved mood and reduced despair in subjects treated with ayahuasca. This highlights the potential of psychedelics in addressing brain disorders within internal medicine and psychology.
Abstract
Abstract not available from OpenAlex