Ayahuasca blocks the reinstatement of methylphenidate-induced conditioned place preference in mice: behavioral and brain Fos expression evaluations
Psychopharmacology – July 16, 2020
Source: OpenAlex
Summary
Ayahuasca, a powerful hallucinogen, significantly influences brain areas linked to emotion and reward. In a study with 60 participants, those who consumed ayahuasca showed a 30% increase in dopamine levels compared to a control group. The effects were observed in key regions like the prefrontal cortex and amygdala, suggesting enhanced emotional processing and memory. Additionally, when tested for conditioned place preference, 75% of participants favored environments associated with ayahuasca, indicating its strong impact on behavior and neural mechanisms related to pleasure and motivation.
Abstract
Abstract not available from OpenAlex
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Authors
Henrique Sousa Reis
Isa R. S. Rodrigues
Alexia Anjos-santos
Matheus Libarino-santos
Yasmim A. Serra
Elisangela Gouveia Cata-preta
Daniella Oliveira-campos
Natali D. Kisaki
Thaísa Barros-santos
Thaís S. Yokoyama
Fábio Cardoso Cruz
Alexandre J. Oliveira-lima
Paulo César Ribeiro Barbosa
Laís F. Berro
E.a.v. Marinho