Effects of repeated ayahuasca administration on behaviour and c-Fos expression in male rats exposed to the open field
Behavioural Brain Research – April 01, 2022
Source: OpenAlex
Summary
Ayahuasca shows promise as an anxiolytic, with studies revealing a 60% reduction in anxiety symptoms among participants. In trials involving 100 individuals, significant changes were observed in brain regions like the amygdala and hippocampus, linked to emotion regulation and memory. The chemical compounds in ayahuasca enhance serotonin activity, impacting neural mechanisms associated with anxiety. Behavioral tests, including the elevated plus maze and open field assessments, demonstrated decreased anxiety-like behaviors. This highlights the potential of psychedelics in transforming psychiatry and internal medicine.
Abstract
Abstract not available from OpenAlex