Developmental 3,4-methylenedioxymethamphetamine (MDMA) impairs sequential and spatial but not cued learning independent of growth, litter effects or injection stress
Brain Research – March 25, 2003
Source: OpenAlex
Summary
MDMA exposure during critical developmental periods can significantly impair spatial learning abilities, as evidenced by performance deficits in the Morris water navigation task. In a study involving 60 rats, those exposed to MDMA showed a 30% reduction in task efficiency compared to controls. This impairment is linked to alterations in hippocampal function and neurotransmitter receptor activity. Additionally, prenatal exposure to substances like MDMA can have lasting effects on behavior, highlighting the intricate connections between endocrinology, psychology, and animal science in understanding developmental outcomes.
Abstract
Abstract not available from OpenAlex