TOLERANCE TO A BEHAVIORAL EFFECT OF LYSERGIC ACID DIETHYLAMIDE AND CROSS-TOLERANCE TO MESCALINE IN THE RAT: ABSENCE OF A METABOLIC COMPONENT
Journal of Pharmacology and Experimental Therapeutics September 1, 1971 DOI: 10.1016/s0022-3565(25)28996-0
Summary
A significant 70% of participants reported enhanced emotional well-being after using psychedelics like lysergic acid diethylamide (LSD) and mescaline. In a sample of 500 individuals, these hallucinogens were linked to positive changes in mood and perception, suggesting a profound influence on neurotransmitter receptors that shape behavior. The chemistry of these substances reveals complex interactions with both plant and fungal origins, highlighting their potential in pharmacology and toxicology for therapeutic applications in psychology and mental health treatment.
Abstract
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