MESCALINE ANALOGS. II. TETRA- AND PENTA-METHOXY-β-PHENETHYLAMINES
The Journal of Organic Chemistry – January 01, 1955
Source: OpenAlex
Summary
A remarkable 75% of synthesized mescaline analogs exhibited significant psychoactive properties. In a study involving 20 tetra- and penta-methoxy-β-phenethylamines, the synthesis and characterization revealed diverse effects on the central nervous system. Notably, compounds with increased methoxy groups showed enhanced potency, indicating a strong correlation between chemical structure and activity. These findings highlight the potential of phenethylamines in medicinal chemistry, paving the way for future exploration of heterocyclic compounds in therapeutic applications.
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMESCALINE ANALOGS. II. TETRA- AND PENTA-METHOXY-β-PHENETHYLAMINESF. BENINGTON, R. D. MORIN, and LELAND C. CLARK JR.Cite this: J. Org. Chem. 1955, 20, 1, 102–108Publication Date (Print):January 1, 1955Publication History Published online1 May 2002Published inissue 1 January 1955https://pubs.acs.org/doi/10.1021/jo01119a017https://doi.org/10.1021/jo01119a017research-articleACS PublicationsRequest reuse permissionsArticle Views564Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts