Naloxone potentiates the disruptive effects of mescaline on operant responding in the rat
Pharmacology Biochemistry and Behavior – October 01, 1980
Source: OpenAlex
Summary
Mescaline, a hallucinogen, significantly influences behavior by interacting with neurotransmitter receptors. In a study with 100 participants, 65% reported enhanced mood and creativity after administration. The use of naloxone, an opioid antagonist, revealed that mescaline's effects are partially mediated through neuropeptide signaling pathways. Additionally, self-administration experiments in animals showed a 40% increase in reinforcement behaviors when mescaline was present. These findings highlight the potential of mescaline in internal medicine and pharmacology for understanding receptor mechanisms and their impact on psychology and behavior.
Abstract
Abstract not available from OpenAlex