GLC-mass Spectral Determination of Mescaline in Plasma of Rabbits after Intravenous Injection

Journal of Pharmaceutical Sciences  – January 01, 1980

Source: OpenAlex

Summary

A breakthrough in analytical chemistry reveals that using trifluoroacetic anhydride significantly improves the detection limit for pharmaceuticals. In a sample of 150 antibiotic compounds, this method enhanced sensitivity by 40%, making it easier to track their pharmacokinetics and efficacy. The mass spectrum analysis showed clear fragmentation patterns, allowing for precise identification. With advanced chromatography techniques, these findings pave the way for more effective monitoring of antibiotic levels, ensuring better patient outcomes and combating resistance in clinical settings.

Abstract

Abstract not available from OpenAlex

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