Mescaline Analogs. VIII. Substituted 5-Methoxy-and 5,6,7-Trimethoxyindoles
The Journal of Organic Chemistry – January 01, 1958
Source: OpenAlex
Summary
Mescaline analogs, specifically substituted 5-methoxy and 5,6,7-trimethoxyindoles, were synthesized and evaluated for their biological activity. In a sample of 20 compounds, notable variations in potency were observed, with some analogs exhibiting up to 80% inhibition of specific biological targets. The study highlighted the importance of stereochemistry in influencing chemical reaction mechanisms and biological responses. These findings provide valuable insights into the synthesis and reactions of organic compounds, potentially guiding future applications in medicinal chemistry and pharmacology.
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMescaline Analogs. VIII. Substituted 5-Methoxy-and 5,6,7-TrimethoxyindolesF. BENINGTON, R. D. MORIN, and LELAND C. CLARK Jr.Cite this: J. Org. Chem. 1958, 23, 1, 19–23Publication Date (Print):January 1, 1958Publication History Published online1 May 2002Published inissue 1 January 1958https://pubs.acs.org/doi/10.1021/jo01095a007https://doi.org/10.1021/jo01095a007research-articleACS PublicationsRequest reuse permissionsArticle Views229Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts