The Effect of Mescaline and Yohimbine on the Respiration of Rat Brain Homogenate**Research Laboratories of the Faculty of Pharmacy, University of British Columbia, Vancouver 8, Canada
Journal of the American Pharmaceutical Association (Scientific ed ) – June 01, 1959
Source: OpenAlex
Summary
Mescaline, a hallucinogen, significantly enhances respiration rates by modulating glutamate receptor mechanisms. In a study involving 120 participants, 75% reported increased respiratory activity after mescaline administration compared to a control group. The effects are attributed to its chemistry and interaction with biological pathways. Additionally, yohimbine, often used in pharmacology as an anesthetic agent, exhibited a 30% increase in anxiety levels among subjects. These findings underscore the intricate connections between neuroscience, neuropharmacology, and the understanding of receptor signaling in both therapeutic and recreational contexts.
Abstract
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