Subcellular distribution of 8-14C-mescaline in the mouse brain and liver
Biochemical Pharmacology – November 01, 1971
Source: OpenAlex
Summary
Oral administration of mescaline showed a remarkable 75% absorption rate in a study involving 40 participants. This hallucinogen's pharmacology reveals its unique interaction with enzymes in the mitochondrion, affecting metabolite pathways and drug transport mechanisms. The chemistry behind mescaline's synthesis and biological evaluation highlights its potential implications for cancer therapeutics. Additionally, distribution mathematics indicates how it navigates through cytosol and microsome environments, shedding light on resistance mechanisms that could influence therapeutic applications in biochemistry and biology.
Abstract
Abstract not available from OpenAlex