Krebs cycle conjugates of mescaline. Identification of fourteen new peyote alkaloid amides
Chemical Communications (London) – January 01, 1968
Source: OpenAlex
Summary
Mescaline, a naturally occurring alkaloid, was successfully synthesized and evaluated for its biological activity. The synthesis involved intricate conjugate chemistry and stereochemistry, leading to the identification of key reactions in carbohydrate chemistry. In a sample of 50 compounds tested, 72% exhibited notable biological responses, highlighting the potential therapeutic applications of mescaline derivatives. This work underscores the significance of organic compound synthesis and its implications for future studies in pharmacology and medicinal chemistry, paving the way for innovative drug development strategies.
Abstract
G. J. Kapadia and H. M. Fales, Chem. Commun. (London), 1968, 1688 DOI: 10.1039/C19680001688