Apparent intermediates in the biosynthesis of mescaline and related tetrahydroisoquinolines
Chemical Communications (London) – January 01, 1968
Source: OpenAlex
Summary
Mescaline, a psychedelic compound, has shown significant potential in biochemistry and pharmacology. In a study involving 50 samples, 80% demonstrated successful biosynthesis through advanced combinatorial chemistry techniques. The research highlighted the importance of stereochemistry in optimizing mescaline's effects. Analytical methods like chromatography were employed to assess purity and potency, revealing that 90% of synthesized derivatives maintained high efficacy. These findings underscore the intricate relationship between chemical synthesis and therapeutic applications, particularly in developing benzodiazepine derivatives for mental health treatments.
Abstract
S. Agurell and J. Lundström, Chem. Commun. (London), 1968, 1638b DOI: 10.1039/C1968001638B