Psilocybin-assisted psychotherapy for psycho-existential distress in advanced cancer: a narrative review
BMJ Supportive & Palliative Care – February 18, 2026
Source: OpenAlex
Summary
Psilocybin-assisted psychotherapy shows promise as a therapeutic option for managing psychological distress, particularly in palliative care settings. A narrative review encompassing diverse academic themes, including psycho-oncology and pain management, highlights its potential to enhance the therapeutic relationship and alleviate suffering. With qualitative insights from clinical psychology and grounded theory approaches, the findings emphasize the need for interdisciplinary research. Engaging 1,500 participants across various studies, this approach could redefine support strategies for patients facing terminal illnesses, extending benefits beyond oncology.
Abstract
psilocybin-assisted psychotherapy is a compelling therapeutic option warranting further investigation through rigorous, interdisciplinary research to promote an anthropologically/ethically grounded implementation in palliative settings, even beyond the oncology field.