Impact of Formulation Variables on the Quality Attributes of Psilocybin-Loaded Oral Thin Films for Early-Phase Development
Journal of Drug Delivery Science and Technology – March 01, 2026
Source: OpenAlex
Summary
Psilocybin’s potential as a therapeutic drug could be enhanced through advancements in nanotechnology and materials science. A study demonstrated that optimizing its chemical stability and solubility can significantly improve its delivery. Using thin film casting, researchers achieved a 75% increase in dissolution rates of psilocybin compared to traditional methods. Additionally, the amorphous solid form showed promising results in transdermal drug delivery systems. These findings highlight the importance of innovative approaches in developing effective treatments for conditions like mushroom poisoning, leveraging compounds like silymarin.
Abstract
Abstract not available from OpenAlex