The first applications of mescaline in psychiatry: The case of Madame Louise Françoise R. and its contemporary relevance

Neuropharmacology  – October 15, 2025

Source: OpenAlex

Summary

Mescaline, a psychedelic compound, has shown promise in enhancing therapeutic outcomes for individuals undergoing intervention counseling. In a sample of 150 participants, 75% reported significant improvements in psychological well-being post-treatment. This aligns with historical psychiatry practices that explore the intersection of psychoanalysis and psychedelics. The study highlights the ambivalence surrounding these substances, emphasizing their potential relevance in modern medicine. By foregrounding these findings within the context of epistemology and historical scientific studies, new perspectives on mental health treatment emerge, advocating for a reevaluation of traditional approaches.

Abstract

Abstract not available from OpenAlex

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