Exposure to psilocin, the active metabolite of psilocybin, leads to increased structural complexity and stronger synaptic connections in human neurons derived from stem cells. This suggests that psychedelics may enhance neuroplasticity in human induced pluripotent stem cell-derived cortical neurons.
Study at a glance
Population
human neurons derived from stem cells
Key finding
Psilocin exposure results in increased structural complexity and stronger synaptic connections in human neurons.
Abstract
Human neurons derived from stem cells show increased structural complexity and stronger synaptic connections after exposure to psilocin, the active metabolite of the psychedelic psilocybin.