Psilocybin as a Tool in the Management of Palliative Care: An Historical, Pharmacological and Clinical Approach
Andrés David Turizo Smith, Natalia Jaramillo, Diana Milena Berrío Cuartas
Medical & Clinical Case Reports Journal May 19, 2025 Peer reviewed DOI: 10.51219/mccrj/andres-david-turizo-smith/233 via OpenAlex
Summary
Psilocybin, a psychedelic compound found in certain mushrooms, may improve the quality of life for patients in palliative care by reducing psychological distress and enhancing emotional well-being. This review explores the historical context, pharmacokinetics, pharmacodynamics, legal status, and future prospects of psilocybin in palliative care settings.
Study at a glance
| Design | review |
|---|---|
| Key finding | Psilocybin has potential to improve the quality of life in palliative care by reducing psychological distress and enhancing emotional well-being. |
Abstract
Psilocybin, a psychedelic compound in certain mushrooms, has been used for centuries in spiritual ceremonies and neuropsychiatric therapy.Despite its stigmatization as a Schedule I substance in 1970, research into psilocybin has resurged since the early 2000s, particularly in psychiatry and palliative care.This review examines psilocybins potential to improve the quality of life in palliative care by reducing psychological distress and enhancing emotional well-being.The discussion includes its historical context, pharmacokinetics, pharmacodynamics, legal status and future perspectives in palliative care.