Ketamine-induced cystitis: A case report and literature review.
Radiology case reports – December 01, 2024
Source: PubMed
Summary
Chronic recreational ketamine use can trigger severe bladder damage, as revealed in a striking medical case. A patient's daily ketamine habit led to cystitis with symptoms including blood in urine and bladder thickening. Through specialized ureteropyeloscopy, doctors confirmed extensive urinary tract damage. After stopping ketamine use and receiving targeted treatment, the patient recovered successfully, highlighting how early intervention can reverse drug-induced bladder problems.
Abstract
Ketamine, a dissociative anesthetic drug, has gained popularity as a recreational substance, particularly among young adults. However, chronic ketamine abuse can lead to various complications including ketamine-induced cystitis. We present the case of a 46-year-old Caucasian male with a history of HIV infection and daily recreational ketamine use for 7 months, who was admitted to the emergency room with hypogastric pain and hematuria. Laboratory examinations and contrast-enhanced abdominal CT tomography revealed significant irregular circumferential thickening of both ureters, substantial bilateral pyeloureteral ectasia, and a bladder with markedly thickened walls. Bilateral flexible ureteropyeloscopy, bladder transurethral resection, and bladder fulguration were performed, and pathology confirmed the diagnosis of ketamine-induced cystitis. Treatment consisted of ketamine withdrawal, pain relief, and support from psychiatrists and urologists. The patient's symptoms improved and he was discharged without complications. This case highlights the importance of recognizing the potential adverse effects of recreational ketamine use and the need for a multidisciplinary approach to managing ketamine-induced cystitis. Further research is necessary to elucidate the precise mechanisms underlying this condition and develop effective prevention and treatment strategies.