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The potential role of lysergic acid diethylamide for psychological assisted therapy: A meta‐analysis of randomised controlled trials in healthy volunteers

Hang Li, Yi Zhong, Siyuan Yang, Jiahe Wang, Xiang Li, Jianguo Xu, Heng Gao, Gang Chen

Human psychopharmacology November 5, 2021 DOI: 10.1002/hup.2825 via Semantic Scholar

Summary

Lysergic acid diethylamide (LSD) produces pronounced subjective drug effects, increases blood pressure, heart rate, and body temperature, and causes side effects in healthy individuals, according to a meta-analysis of existing studies. The analysis quantifies the magnitude of these physiological and psychological responses, supporting the renewed interest in using LSD in psychiatric research and therapy.

Study at a glance

Characteristics Meta-analysis Randomized Peer reviewed
Population Healthy subjects
Keywords Medicine Psychology
Citations 7
Key finding LSD significantly alters subjective drug effects, blood pressure, heart rate, body temperature, and side effects in healthy individuals.

Abstract

In recent years, interest in using lysergic acid diethylamide (LSD) in psychiatric research and corresponding therapy has increased rapidly. In this meta‐analysis, we explored the effects of LSD on healthy subjects with respect to subjective drug effects, blood pressure, heart rate, body temperature and side effects.

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