Drugie życie psychodelików
Krystyna Gołembiowska, K. Kamińska
Kosmos August 8, 2024 DOI: 10.36921/kos.2024_2994 via Semantic Scholar
Summary
Classic psychedelics such as psilocybin, mescaline, DMT, and LSD alter consciousness, perception, and produce hallucinations through serotonergic pharmacodynamic effects. These compounds profoundly affect neuroplasticity—altering neuronal structure and function. Their psychoplastogenic properties suggest potential for treating depression, neurodegenerative disorders like Alzheimer's disease, recovery after stroke, and schizophrenia. The role of microdosing, defined as 10% of the dose that elicits psychedelic effects, requires extensive further investigation.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Keywords | Medicine Psychology |
| Key finding | Classic psychedelics have psychoplastogenic properties that suggest potential for treating depression, Alzheimer's disease, stroke recovery, and schizophrenia, but microdosing requires further investigation. |
Abstract
Psychedelics known for mankind from millennia are class of compounds that alter consciousness, affect perception and produce hallucinations. Classic psychedelics such as psilocybin, mescaline, dimethyltryptamine (DMT) and lysergic acid diethylamide (LSD) have pharmacodynamic serotonergic effects. They are known to exert profound effects on neuroplasticity i.e. alteration of neuronal structure and function. The psychoplastogenic properties led to their potential in treatment of depression, neurodegenerative disorders such as Alzheimer’s Disease, recovery after stroke and in schizophrenia. The role of microdosing regarded as 10% of the dose that elicits psychedelic effects needs extensive investigation.