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Hepatitis B Vaccination in Psychiatric patients in Morocco

E. Prades, A. Torres, P. Díez, A. Miranda, I. Franco, J. Miranda, B. Zineb, T. Aicha, K. Imane, L. Fouad, O. Abderrazak, C. Navarro, I. Salas, L. San, A. Fariña, A. B. Idarraga, U. L. Puentes, B. S. Martínez, R. L. Brokate, T. De, Azua Aspizua, E. Cos, U. O. Pozas, D. Gomes, F. Silveira, R. Freitas

European psychiatry March 1, 2023 DOI: 10.1192/j.eurpsy.2023.1586 via Semantic Scholar

Summary

A 43-year-old woman experienced a psychotic episode two days after her third ayahuasca session in a ritual context. Symptoms included loss of consciousness, convulsions, weakness and numbness on the right side, and delusions of electromagnetic fields draining her life force. She required four days in intensive care, then was hospitalized and treated with risperidone 1.5 mg, leading to complete symptom remission. The case aligns with other reports of ayahuasca-induced psychosis, though with less intensity and duration. The rising use of ayahuasca in non-controlled and recreational settings warrants clinical awareness.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population 43-year-old woman
Keywords Medicine
Citations 1
Key finding Ayahuasca intake in a ritual context was associated with a psychotic episode featuring convulsions, perceptual alterations, and delusions, which fully resolved with risperidone treatment.

Abstract

Introduction Ayahuasca is a traditional brew containing the psychedelic 5-DMT (a tryptamine that acts as a 5HT2A-R agonist) used to achieve non-ordinary states of consciousness, with a long tradition among various cultures in ritual and therapeutic contexts. Ayahuasca is being studied as potential treatment in Mental Health, which has led to non-controlled and recreational use. This has led to a rise in the description of side effects, such as substance-induced psychosis. Objectives To describe a case of a possible psychotic episode related to the intake of ayahuasca brew in a ritual context. Methods Clinical assesment and bibliographic review of pertinent literature. Results We will present the case of a 43 year old woman, who participated in three ayahuasca sessions in three consecutive months. Two days after the last session, she suffered and episode of loss of consciousness, convulsions, loss of streng and paraesthesia in right forearm and righr side of the face and head; and apparition of perceptual alterations and delusions that she did not experience during the trip. Such alterations included the perception of electromagnetic fields (EMF) robbing her of her vital energy and lifeforce. She required ICU treatment for four days, after which se was hospitalized in Internal Medicine Unit and was assessed by Mental Health team. Though the symptoms were coherent with the previous beliefs of the patient, they were clearly exacerbated and interfered with her normal and previous functioning. She was treated with risperidone 1,5 mg, with complete symptom remission. Conclusions The case presented is consistent with other reports of ayahuasca-induced psychotic symptoms, though with less intensity and duration. We discuss prevalence and repercussions of the rising use of this powerful substance; that must be taken into consideration by clinicians worldwide. Disclosure of Interest None Declared

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