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Dissociative identity precipitated by emergence from general anesthesia: A case report and analytical framework

Gregory W. Kirschen, Mary E. Shorey, Joan C. Han, Idris Leppla, Courtney Masear, Jennifer Robinson

Psychiatry Research Case Reports July 26, 2023 DOI: 10.1016/j.psycr.2023.100152 via OpenAlex

Summary

A woman with a history of childhood sexual abuse and a past suicide attempt developed a dissociative identity episode upon emerging from anesthesia. The episode lasted 90 minutes and resolved on its own; she was discharged safely two days later. This case suggests that anesthesia can be a trigger for dissociative identity disorder (DID) in vulnerable individuals, adding to known psychosocial precipitants. The authors propose a mechanism involving anesthesia's effects on functional brain connectivity as a unifying hypothesis.

Study at a glance

Characteristics Case report Peer reviewed
Sample size 1
Population A woman with a history of childhood sexual abuse and past suicide attempt
Keywords Dissociative identity disorder Dissociative disorders Psychosocial Multiple personality disorder Sexual abuse
Key finding Anesthesia emergence can precipitate a dissociative identity episode in a person with a history of childhood abuse and suicide attempt.

Abstract

Background: Dissociative identity disorder (DID) is a complex and controversial psychiatric condition in which one person maintains at least two separate and distinct personalities. Patients with DID often report a history of childhood abuse and may have other comorbid psychiatric conditions. Psychosocial stressors may be triggers for DID inception or recurrence. While anesthetic agents, in particular ketamine, may induce a temporary dissociative state, it has not yet been reported that anesthesia can precipitate a dissociative identity. Case report: We report a case of a woman with a history of childhood sexual abuse and past suicide attempt who experienced an episode of dissociative identity on emergence from anesthesia. The episode resolved within 90 minutes and the patient was discharged home safely on hospital day two. Conclusion: This case adds to the literature of potentially precipitating factors of DID and we provide a unifying mechanistic hypothesis linking anesthesia to functional brain connectivity.

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