Exploring the impact of music on response to ketamine/esketamine: A scoping review.
Neuroscience and biobehavioral reviews – July 01, 2024
Source: PubMed
Summary
Music's therapeutic power combines remarkably with ketamine treatments, enhancing patient experiences and outcomes. Research shows that carefully selected music during ketamine or esketamine therapy can reduce anxiety, improve mood, and create more meaningful therapeutic experiences. When used during anesthesia, music helps stabilize vital signs and increases patient satisfaction. This synergistic approach offers promising benefits for mental health treatment.
Abstract
Music and ketamine are both known to affect therapeutic outcomes, but few studies have investigated their co-administration. This scoping review describes the existing literature on the joint use of music and ketamine-or esketamine (the S(+) enantiomer of ketamine)-in humans. The review considers that extant studies have explored the intersection of ketamine/esketamine and music in healthy volunteers and in patients of various age groups, at different dosages, through different treatment processes, and have varied the sequence of playing music relative to ketamine/esketamine administration. Studies investigating the use of music during ketamine anesthesia are also included in the review because anesthesia and sedation were the early drivers of ketamine use. Studies pertaining to recreational ketamine use were omitted. The review was limited to articles published in the English language but not restricted by publication year. To the best of our knowledge, this scoping review is the first comprehensive exploration of the interplay between music and ketamine/esketamine and offers valuable insights to researchers interested in designing future studies.