Addressing blinding in classic psychedelic studies with innovative active placebos.
Int J Neuropsychopharmacol – April 01, 2025
Source: PubMed Central
Summary
Traditional placebos fall short when testing psychedelic medicines - participants easily guess if they received the real drug. Researchers developed new active placebos that mimic some psychedelic effects while maintaining study integrity. This breakthrough helps validate therapeutic benefits of psychedelics by enabling proper controlled trials without compromising scientific rigor.
Abstract
Addressing blinding in classic psychedelic studies with innovative active placebos.